Bioactive algal metabolites in Ambystoma maculatum and A. mexicanum tail regeneration

Salamanders are vertebrates that can regenerate many tissues including limbs, parts of the brain, spinal cord, and heart. Unlike human healing, tissue patterning is recovered during salamander regeneration. We screened whole-cell algal symbionts (Oophila amblystomatis) for their regenerative effect on embryonic yellow spotted salamanders (Ambystoma maculatum) and axolotl (A. mexicanum). Observed increased regrowth rates mark a rare regeneration discovery that will lead to better understanding of regeneration science.